Article
Molecular pathology of RUNX3 in human carcinogenesis.
Biochimica et biophysica acta - 1 Dec 2009
Subramaniam Manish Mani, Chan Jason Yongsheng, Yeoh Khay Guan, Quek Timothy, Ito Kosei, Salto-Tellez Manuel
Abstract excerpt
A major goal of molecular biology is to elucidate the mechanisms underlying cancer development and progression in order to achieve early detection, better diagnosis and staging and novel preventive and therapeutic strategies. We feel that an understanding of Runt-related transcription factor 3 (RUNX3)-regulated biological pathways will directly impact our knowledge of these areas of human carcinogenesis. The...
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