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Article

Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development

29 Feb 2008

Abstract excerpt

Bone morphogenic proteins (BMPs) are members of the TGFB growth factor superfamily with well-described functions in bone formation. Although disrupted BMP signalling in tumor development has more recently been investigated, a role for BMP3 in colorectal cancer (CRC) has remained largely unexplored. The aim of this study was to investigate BMP3 disruption in CRCs in relation to both the traditional and serrated...

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Share to Colorectal Cancer Screening and Detection
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Share to TGF-β signaling in diseases

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PMID: 18311777
DOI: 10.1002/gcc.20552

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