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Article

Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.

PloS one - 21 Apr 2010

Willberg Christian B, Garrison Keith E, Jones R Brad, Meiklejohn Duncan A, Spotts Gerald, Liegler Teri J, Ostrowski Mario A, Karlsson Annika C, Hecht Frederick M, Nixon Douglas F

Abstract excerpt

BACKGROUND: The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele. METHODOLOGY/PRINCIPAL FINDINGS: Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally during early HIV-1 infection in 16 HLA-B*35+ individuals. Subjects expressing HLA-B*35-Px alleles showed no difference...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to HLA-B35 Antigen

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Source

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Identifiers

PMID: 20422053
DOI: 10.1371/journal.pone.0010249
PMCID: PMC2858076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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