Article
Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles.
Viral immunology - 1 Jun 2011
Peretz Yoav, Marra Olivia, Thomas Réjean, Legault Danielle, Côté Pierre, Boulassel Mohamed-Rachid, Rouleau Danielle, Routy Jean-Pierre, Sékaly Rafick-Pierre, Tsoukas Christos M, Tremblay Cécile, Bernard Nicole F
Abstract excerpt
Expression of major histocompatibility complex (MHC) class I alleles such as B*57 and B*27 are associated with slow HIV disease progression. HIV-specific immune responses in slow progressors (SP) are characterized by a poly-functional profile. We previously observed within infected subjects that HIV peptide-specific responses could differ from each other in their functional composition. We investigate here...
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