Article
Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index.
The American journal of clinical nutrition - 1 May 2010
Zillikens M Carola, van Meurs Joyce B J, Rivadeneira Fernando, Hofman Albert, Oostra Ben A, Sijbrands Eric J G, Witteman Jacqueline C M, Pols Huibert A P, van Duijn Cornelia M, Uitterlinden André G
Abstract excerpt
BACKGROUND: Genetic variation in SIRT1 has been associated with body mass index (BMI) and risk of obesity. SIRT1 may be influenced by diet. OBJECTIVE: We studied the gene-diet interaction on BMI at the SIRT1 locus. DESIGN: In 4575 elderly men and women in the population-based Rotterdam Study, the...
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