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Article

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study.

BMC medical genetics - 12 Nov 2008

Weyrich Peter, Machicao Fausto, Reinhardt Julia, Machann Jürgen, Schick Fritz, Tschritter Otto, Stefan Norbert, Fritsche Andreas, Häring Hans-Ulrich

Abstract excerpt

BACKGROUND: Sirtuin1 (SIRT1) regulates gene expression in distinct metabolic pathways and mediates beneficial effects of caloric restriction in animal models. In humans, SIRT1 genetic variants associate with fasting energy expenditure. To investigate the relevance of SIRT1 for human metabolism an...

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Source

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Identifiers

PMID: 19014491
DOI: 10.1186/1471-2350-9-100
PMCID: PMC2626584

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19014491-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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