Article
Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change.
Gene - 5 Dec 2016
Higashibata Takahiro, Wakai Kenji, Naito Mariko, Morita Emi, Hishida Asahi, Hamajima Nobuyuki, Hara Megumi, Suzuki Sadao, Hosono Satoyo, Takashima Naoyuki, Ohnaka Keizo, Takada Akihiko, Mikami Haruo, Watanabe Yoshiyuki, Uemura Hirokazu, Kubo Michiaki, Tanaka Hideo
Abstract excerpt
SIRT1 acts as a cellular sensor to detect energy availability and modulates fat and glucose metabolism. This study assessed the effects of self-reported calorie restriction (CR) and exercise on correlations between SIRT1 polymorphisms and body mass index (BMI) and long-term weight change. This cross-sectional study enrolled 4023 subjects aged 35-69years (1847 men and 2176 women) selected from participants in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.