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Article

Association study of sirtuin 1 polymorphisms with bone mineral density and body mass index.

Archives of medical research - 1 Jul 2012

Zarrabeitia María T, Valero Carmen, Martín-Escudero Juan C, Olmos José M, Bolado-Carrancio Alfonso, de Sande-Nacarino Eva L, Rodríguez-Rey José C, Sainz Jesús, Riancho José A

Abstract excerpt

BACKGROUND AND AIMS: Sirtuin 1, encoded by the SIRT1 gene, is an emerging modulator of carbohydrate and lipid metabolism and may also influence the differentiation of bone cells. Our objective was to test the hypothesis that polymorphisms of SIRT1 are associated with body mass index (BMI) and bone mineral density (BMD). METHODS: We carried out a cross-sectional genetic association study with genotyping of ten...

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Source

Identifiers

PMID: 22824213
DOI: 10.1016/j.arcmed.2012.06.012

Genes

SIRT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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