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Article

Mutation of the DEAD-box helicase belle downregulates the cyclin-dependent kinase inhibitor Dacapo.

Cell cycle (Georgetown, Tex.) - 1 Mar 2010

Ambrus Aaron M, Frolov Maxim V

Abstract excerpt

The retinoblastoma protein (pRB) negatively regulates cell proliferation by limiting the activity of the family of E2F transcription factors. In Drosophila, mutation of the DEAD-box helicase belle (bel) relieves an E2F/pRB induced G(1) cell cycle arrest; however, the mechanism of this rescue is u...

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Identifiers

PMID: 20160476
DOI: 10.4161/cc.9.5.10953
PMCID: PMC3015103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20160476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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