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Article

Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.

PLoS genetics - 17 Nov 2006

Morris Erick J, Michaud William A, Ji Jun-Yuan, Moon Nam-Sung, Rocco James W, Dyson Nicholas J

Abstract excerpt

Retinoblastoma protein and E2-promoter binding factor (E2F) family members are important regulators of G1-S phase progression. Deregulated E2F also sensitizes cells to apoptosis, but this aspect of E2F function is poorly understood. Studies of E2F-induced apoptosis have mostly been carried out in tissue culture cells, and the analysis of the factors that are important for this process has been restricted to the...

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Identifiers

PMID: 17112319
DOI: 10.1371/journal.pgen.0020196
PMCID: PMC1636698

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.PMID 17112319Read ↗

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