Article
Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.
The EMBO journal - 4 Jan 1999
de la Luna S, Allen K E, Mason S L, La Thangue N B
Abstract excerpt
Transcription factor E2F plays an important role in orchestrating early cell cycle progression through its ability to co-ordinate and integrate the cell cycle with the transcription apparatus. Physiological E2F arises when members of two distinct families of proteins interact as E2F-DP heterodime...
Topics
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Cell Cycle
- Cell Cycle Proteins
- Cell Line
- DNA-Binding Proteins
- Dimerization
- Drosophila Proteins
- Drosophila melanogaster
- E2F Transcription Factors
- Growth Inhibitors
- Humans
- Intercellular Signaling Peptides and Proteins
- Mice
- Models, Biological
- Molecular Sequence Data
- Mutation