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Article

Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.

The EMBO journal - 4 Jan 1999

de la Luna S, Allen K E, Mason S L, La Thangue N B

Abstract excerpt

Transcription factor E2F plays an important role in orchestrating early cell cycle progression through its ability to co-ordinate and integrate the cell cycle with the transcription apparatus. Physiological E2F arises when members of two distinct families of proteins interact as E2F-DP heterodimers, in which the E2F component mediates transcriptional activation and the physical interaction with pocket proteins,...

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Identifiers

PMID: 9878064
DOI: 10.1093/emboj/18.1.212
PMCID: PMC1171116

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Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.PMID 9878064Read ↗

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