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Article

dDP is needed for normal cell proliferation.

Molecular and cellular biology - 1 Apr 2005

Frolov Maxim V, Moon Nam-Sung, Dyson Nicholas J

Abstract excerpt

To gain insight into the essential functions of E2F, we have examined the phenotypes caused by complete inactivation of E2F and DP family members in Drosophila. Our results show that dDP requires dE2F1 and dE2F2 for DNA-binding activity in vitro and in vivo. In tissue culture cells and in mutant animals, the levels of dE2F and dDP proteins are strongly interdependent. In the absence of dDP, the levels of dE2F1...

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Identifiers

PMID: 15798191
DOI: 10.1128/MCB.25.8.3027-3039.2005
PMCID: PMC1069608

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Source receipt: pubmed, retrieved 7 Sept 2026.

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dDP is needed for normal cell proliferation.PMID 15798191Read ↗

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