Article
Drosophila DDX3/Belle Exerts Its Function Outside of the Wnt/Wingless Signaling Pathway.
PloS one - 1 Jan 2016
Jenny Fabian H, Basler Konrad
Abstract excerpt
The helicases human DDX3 and Drosophila Belle (Bel) are part of a well-defined subfamily of the DEAD-box helicases. Individual subfamily-members perform a myriad of functions in nuclear and cytosolic RNA metabolism. It has also been reported that DDX3X is involved in cell signaling, including IFN-α and IFN-β inducing pathways upon viral infection as well as in Wnt signaling. Here we used a collection of...
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