Article
PLAUR polymorphisms and lung function in UK smokers.
BMC medical genetics - 31 Oct 2009
Stewart Ceri E, Hall Ian P, Parker Stuart G, Moffat Miriam F, Wardlaw Andrew J, Connolly Martin J, Ruse Charlotte, Sayers Ian
Abstract excerpt
BACKGROUND: We have previously identified Urokinase Plasminogen Activator Receptor (PLAUR) as an asthma susceptibility gene. In the current study we tested the hypothesis that PLAUR single nucleotide polymorphisms (SNPs) determine baseline lung function and contribute to the development of Chronic Obstructive Pulmonary Disease (COPD) in smokers. METHODS: 25 PLAUR SNPs were genotyped in COPD subjects and...
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