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Article

Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients.

Allergy - 1 Mar 2017

Portelli M A, Moseley C, Stewart C E, Postma D S, Howarth P, Warner J A, Holloway J W, Koppelman G H, Brightling C, Sayers I

Abstract excerpt

RATIONALE: Genetic polymorphisms in the asthma susceptibility gene, urokinase plasminogen activator receptor (uPAR/PLAUR) have been associated with lung function decline and uPAR blood levels in asthma subjects. Preliminary studies have identified uPAR elevation in asthma; however, a definitive study regarding which clinical features of asthma uPAR may be driving is currently lacking. OBJECTIVES: We aimed to...

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Source

Identifiers

PMID: 27624865
DOI: 10.1111/all.13046

Genes

PLAUR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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