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Article

Association of urokinase-type plasminogen activator with asthma and atopy.

American journal of respiratory and critical care medicine - 1 Jun 2007

Bégin Philippe, Tremblay Karine, Daley Denise, Lemire Mathieu, Claveau Sébastien, Salesse Charleen, Kacel Sabine, Montpetit Alexandre, Becker Allan, Chan-Yeung Moira, Kozyrskyj Anita L, Hudson Thomas J, Laprise Catherine

Abstract excerpt

RATIONALE: Urokinase plasminogen activator (uPA) interacts with its receptor on inflammatory and migrating cells to regulate extracellular matrix degradation, cell adhesion, and inflammatory cell activation. It is necessary for the development of an appropriate immune response and is involved in tissue remodeling. The PLAU gene codes for this enzyme, and is located on 10q24. This region has demonstrated evidence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17363771
DOI: 10.1164/rccm.200607-1012OC

Genes

PLAU
AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of urokinase-type plasminogen activator with asthma and atopy.PMID 17363771Read ↗

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