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Article

The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations.

American journal of respiratory and critical care medicine - 15 Jul 2007

Zhu Guohua, Warren Liling, Aponte Jennifer, Gulsvik Amund, Bakke Per, Anderson Wayne H, Lomas David A, Silverman Edwin K, Pillai Sreekumar G

Abstract excerpt

RATIONALE: Chronic obstructive pulmonary disease (COPD) is a complex disease influenced by multiple genes and environmental factors. A region on chromosome 2q has been shown to be linked to COPD. A positional candidate gene from the chromosome 2q region SERPINE2 (Serpin peptidase inhibitor, clade E [nexin, plasminogen activator inhibitor type 1], member 2), was previously evaluated as a susceptibility gene for...

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Source

Identifiers

PMID: 17446335
DOI: 10.1164/rccm.200611-1723OC

Genes

SERPINE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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