Article
Gene Association Study of the Urokinase Plasminogen Activator and Its Receptor Gene in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2024
Cetinsoy Ozde, Anyanwu Ijeoma, Krishnanand Harikrishnan, Natarajan Gokulakrishnan, Ramachandran Naveen, Thomas Alan, Brookes Keeley J
Abstract excerpt
Background: The role of the innate immune system has long been associated with Alzheimer's disease (AD). There is now accumulating evidence that the soluble Urokinase Plasminogen Activator Receptor pathway, and its genes, PLAU and PLAUR may be important in AD, and yet there have been few genetic association studies to explore this. Objective: This study utilizes the DNA bank of the Brains for Dementia Research...
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