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Article

Rapid exchange of bound ADP on the Staphylococcus aureus replication initiation protein DnaA.

The Journal of biological chemistry - 4 Dec 2009

Kurokawa Kenji, Mizumura Hikaru, Takaki Tohru, Ishii Yumiko, Ichihashi Norikazu, Lee Bok Luel, Sekimizu Kazuhisa

Abstract excerpt

In Escherichia coli, regulatory inactivation of the replication initiator DnaA occurs after initiation as a result of hydrolysis of bound ATP to ADP, but it has been unknown how DnaA is controlled to coordinate cell growth and chromosomal replication in gram-positive bacteria such as Staphylococcus aureus. This study examined the roles of ATP binding and its hydrolysis in the regulation of the S. aureus DnaA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19841480
DOI: 10.1074/jbc.M109.060681
PMCID: PMC2797190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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