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Article

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin.

The Journal of biological chemistry - 28 Mar 2008

Ozaki Shogo, Kawakami Hironori, Nakamura Kenta, Fujikawa Norie, Kagawa Wataru, Park Sam-Yong, Yokoyama Shigeyuki, Kurumizaka Hitoshi, Katayama Tsutomu

Abstract excerpt

Initiation of chromosomal replication and its cell cycle-coordinated regulation bear crucial and fundamental mechanisms in most cellular organisms. Escherichia coli DnaA protein forms a homomultimeric complex with the replication origin (oriC). ATP-DnaA multimers unwind the duplex within the oriC unwinding element (DUE). In this study, structural analyses suggested that several residues exposed in the central...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18216012
DOI: 10.1074/jbc.M708684200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin.PMID 18216012Read ↗

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