Article
Negative control of replication initiation by a novel chromosomal locus exhibiting exceptional affinity for Escherichia coli DnaA protein.
Genes & development - 1 Oct 1998
Kitagawa R, Ozaki T, Moriya S, Ogawa T
Abstract excerpt
Replication of the Escherichia coli chromosome is initiated at a unique site, oriC. Concurrent initiation occurs at all oriC sites present in a cell once, and only once, per cell cycle. A mechanism to ensure cyclic initiation events was found operating through the chromosomal site, datA, a 1-kb s...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Cell Cycle
- Chromosomes, Bacterial
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Mutation
- Phenotype
- Transcription Factors