Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Countermeasures to survive excessive chromosome replication in Escherichia coli.

Current genetics - 1 Feb 2018

Charbon Godefroid, Riber Leise, Løbner-Olesen Anders

Abstract excerpt

In Escherichia coli, like all organisms, DNA replication is coordinated with cell cycle progression to ensure duplication of the genome prior to cell division. Chromosome replication is initiated from the replication origin, oriC, by the DnaA protein associated with ATP. Initiations take place once per cell cycle and in synchrony at all cellular origins. DnaA also binds ADP with similar affinity as ATP and in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Bacterial
Share to DNA Replication
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Genomic Instability

Share to Microbial Viability

Share to Models, Biological

Share to Mutation

Source

Identifiers

PMID: 28664289
DOI: 10.1007/s00294-017-0725-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Countermeasures to survive excessive chromosome replication in Escherichia coli.PMID 28664289Read ↗

Suppressors of DnaA(ATP) imposed overinitiation in Escherichia coli.Semantic proximity Read ↗

Mutant DnaAs of Escherichia coli that are refractory to negative control.Semantic proximity Read ↗

Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein.Semantic proximity Read ↗

Modes of overinitiation, dnaA gene expression, and inhibition of cell division in a novel cold-sensitive hda mutant of Escherichia coli.Semantic proximity Read ↗

Hyperinitiation of DNA replication in Escherichia coli leads to replication fork collapse and inviability.Semantic proximity Read ↗

UV-induced DNA damage disrupts the coordination between replication initiation, elongation and completion.Semantic proximity Read ↗

Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli.Semantic proximity Read ↗

Error-prone DNA polymerases: when making a mistake is the only way to get ahead.Semantic proximity Read ↗

DNA replication in Escherichia coli is initiated by membrane detachment of oriC. A model.Semantic proximity Read ↗

A role for nonessential domain II of initiator protein, DnaA, in replication control.Semantic proximity Read ↗

Lethal effects of a hyperactive dGTP triphosphohydrolase in E. coli.Semantic proximity Read ↗

Error-prone replication for better or worse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.