Article
Association between IL-1B and IL-1RN gene polymorphisms and Chagas' disease development susceptibility.
Immunological investigations - 1 Jan 2009
Cruz-Robles David, Chávez-González Juan Pablo, Cavazos-Quero María Magdalena, Pérez-Méndez Oscar, Reyes Pedro A, Vargas-Alarcón Gilberto
Abstract excerpt
Though it is known that the immune system exerts some influence on the resistance against T. cruzi infection its precise role in this process is not well-understood. Some IL-1B alleles and haplotypes have been associated with susceptibility to inflammatory, autoimmune and infectious diseases. The objective of this study was to determine and compare the distribution of IL-1B and IL-1 receptor antagonist (IL-1RN)...
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