Article
Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes.
BioMed research international - 1 Jan 2013
Ayo Christiane Maria, Dalalio Márcia Machado de Oliveira, Visentainer Jeane Eliete Laguila, Reis Pâmela Guimarães, Sippert Emília Ângela, Jarduli Luciana Ribeiro, Alves Hugo Vicentin, Sell Ana Maria
Abstract excerpt
Chagas disease, which is caused by the flagellate parasite Trypanosoma cruzi, affects 8-10 million people in Latin America. The disease is endemic and is characterised by acute and chronic phases that develop in the indeterminate, cardiac, and/or gastrointestinal forms. The immune response during human T. cruzi infection is not completely understood, despite its role in driving the development of distinct...
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