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Article

Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2010

Torres Orlando A, Calzada José E, Beraún Yasmina, Morillo Carlos A, González Antonio, González Clara I, Martín Javier

Abstract excerpt

Genetic susceptibility to Trypanosoma cruzi infection and the development of cardiomyopathy is complex, heterogeneous, and likely involves several genes. Previous studies have implicated cytokine and chemokine genes in susceptibility to Chagas disease. Here we investigated the association between the interferon-gamma gene (IFNG) +874T/A polymorphism and Chagas disease, focusing on susceptibility and severity....

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Source

Open in PubMed Open full text

Identifiers

PMID: 20359550
DOI: 10.1016/j.meegid.2010.03.009
PMCID: PMC7106279

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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