Article
Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil.
Journal of immunology research - 1 Jan 2017
Reis Pâmela Guimarães, Ayo Christiane Maria, de Mattos Luiz Carlos, Brandão de Mattos Cinara de Cássia, Sakita Karina Mayumi, de Moraes Amarilis Giaretta, Muller Larissa Pires, Aquino Julimary Suematsu, Conci Macedo Luciana, Mazini Priscila Saamara, Sell Ana Maria, Marques Divina Seila de Oliveira, Bestetti Reinaldo Bulgarelli, Visentainer Jeane Eliete Laguila
Abstract excerpt
The aim of this study was to investigate possible associations between genetic polymorphisms of IL17A G197A (rs2275913) and IL17F T7488C (rs763780) with Chagas Disease (CD) and/or the severity of left ventricular systolic dysfunction (LVSD) in patients with chronic Chagas cardiomyopathy (CCC). The study with 260 patients and 150 controls was conducted in the South and Southeast regions of Brazil. The genotyping...
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