Article
MICA and KIR: Immunogenetic Factors Influencing Left Ventricular Systolic Dysfunction and Digestive Clinical Form of Chronic Chagas Disease.
Frontiers in immunology - 1 Jan 2021
Ayo Christiane Maria, Bestetti Reinaldo Bulgarelli, de Campos Junior Eumildo, Ronchi Luiz Sérgio, Borim Aldenis Albaneze, Brandão Cinara Cássia, de Matttos Luiz Carlos
Abstract excerpt
Tissue damage observed in the clinical forms of chronic symptomatic Chagas disease seems to have a close relationship with the intensity of the inflammatory process. The objective of this study was to investigate whether the MICA (MHC class I-related chain A) and KIR (killer cell immunoglobulin-like receptors) polymorphisms are associated with the cardiac and digestive clinical forms of chronic Chagas disease....
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