Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism in the 3' UTR of the IL12B gene is associated with Chagas' disease cardiomyopathy.

Microbes and infection - 1 Jul 2007

Zafra German, Morillo Carlos, Martín Javier, González Antonio, González Clara Isabel

Abstract excerpt

The aim of this study was to investigate the possible influence of a 3' untranslated region (3' UTR) polymorphism of the IL12B gene in susceptibility to Trypanosoma cruzi infection or in the development to cardiomyopathy in Chagas' disease (CD). We determined the IL12B 3' UTR genotypes in a sample of 200 seronegative individuals and 260 serologically positive patients (130 with Chagasic cardiomyopathy and 130...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Chagas Cardiomyopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Interleukin-12 Subunit p40

Share to Polymorphism, Genetic

Share to Trypanosoma cruzi

Source

Identifiers

PMID: 17644387
DOI: 10.1016/j.micinf.2007.04.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism in the 3' UTR of the IL12B gene is associated with Chagas' disease cardiomyopathy.PMID 17644387Read ↗

Interleukin-1 gene cluster polymorphism in chagas disease in a Colombian case-control study.Semantic proximity Read ↗

Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population.Semantic proximity Read ↗

Association between IL-1B and IL-1RN gene polymorphisms and Chagas' disease development susceptibility.Semantic proximity Read ↗

Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy.Semantic proximity Read ↗

Functional IL-10 gene polymorphism is associated with Chagas disease cardiomyopathy.Semantic proximity Read ↗

Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations.Semantic proximity Read ↗

Functional IL18 polymorphism and susceptibility to Chronic Chagas Disease.Semantic proximity Read ↗

A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease.Semantic proximity Read ↗

Evaluation of Apolipoprotein-A1 genetic polymorphisms as biomarkers for Chagas cardiomyopathy in patients from Córdoba, Argentina.Semantic proximity Read ↗

Genetic variants in the chemokines and chemokine receptors in Chagas disease.Semantic proximity Read ↗

IL18 Gene Variants Influence the Susceptibility to Chagas Disease.Semantic proximity Read ↗

Investigation of the role of IL17A gene variants in Chagas disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.