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Article

Preferential loss of maternal alleles in sporadic Wilms' tumour.

Oncogene - 1 Nov 1990

Pal N, Wadey R B, Buckle B, Yeomans E, Pritchard J, Cowell J K

Abstract excerpt

Loss of heterozygosity at loci on the short arm of chromosome 11 has been reported in 31% (11/38) of Wilms' tumours in our series. Lymphoblastoid cell lines were prepared from the parents of 10/11 of the patients showing allele loss in their tumours. In 9 of the cases, where the parental origin of the alleles could be followed, it was the paternal alleles which were retained in the tumour. This preferential loss...

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Identifiers

PMID: 1980007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Preferential loss of maternal alleles in sporadic Wilms' tumour.PMID 1980007Read ↗

Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.Semantic proximity Read ↗

Loss of heterozygosity in Wilms' tumors, studied for six putative tumor suppressor regions, is limited to chromosome 11.Semantic proximity Read ↗

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Differences in patterns of allelic loss between two common types of adult cancer, breast and colon carcinoma, and Wilms' tumor of childhood.Semantic proximity Read ↗

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour.Semantic proximity Read ↗

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.Semantic proximity Read ↗

Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters.Semantic proximity Read ↗

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