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Article

Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.

Oncogene - 1 Jun 1990

Wadey R B, Pal N, Buckle B, Yeomans E, Pritchard J, Cowell J K

Abstract excerpt

Pairs of tumour and normal DNA samples from 38 Wilms' tumour patients have been investigated for loss of heterozygosity using 12 probes from chromosome 11. Allele loss was detected in only 11 cases (31%). Densitometric analysis showed that allele loss was not due to non-disjunction or hemizygous deletion, but rather to mitotic recombination or non-disjunction plus reduplication. Although the development of...

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PMID: 2163053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.PMID 2163053Read ↗

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Genetic mosaicism in normal tissues of Wilms' tumour patients.Semantic proximity Read ↗

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