Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A third Wilms' tumor locus on chromosome 16q.

Cancer research - 1 Jun 1992

Maw M A, Grundy P E, Millow L J, Eccles M R, Dunn R S, Smith P J, Feinberg A P, Law D J, Paterson M C, Telzerow P E

Abstract excerpt

Loss of heterozygosity studies have been used to identify chromosomal regions which are frequently deleted and thus indicate areas which may harbor tumor suppressor genes. As a result, both the WT1 gene located in chromosome 11p13 and an unidentified gene(s) within chromosome 11p15 have been implicated in Wilms' tumorigenesis. Cytogenetic and linkage studies suggest that additional non-chromosome 11 sites are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Deletion
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

Share to DNA, Neoplasm

Share to Genes, Tumor Suppressor

Share to Heterozygote

Share to Pedigree

Source

Identifiers

PMID: 1317258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A third Wilms' tumor locus on chromosome 16q.PMID 1317258Read ↗

Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters.Semantic proximity Read ↗

Clinicopathologic correlates of loss of heterozygosity in Wilm's tumor: a preliminary analysis.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.Semantic proximity Read ↗

Allelotyping in Wilms tumors identifies a putative third tumor suppressor gene on chromosome 11.Semantic proximity Read ↗

Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors.Semantic proximity Read ↗

Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.Semantic proximity Read ↗

Loss of heterozygosity in Wilms' tumors, studied for six putative tumor suppressor regions, is limited to chromosome 11.Semantic proximity Read ↗

Loss of heterozygosity for chromosome region 11p15 in Wilms' tumours is not related to HRAS gene transforming mutations.Semantic proximity Read ↗

Genetic and epigenetic alterations on the short arm of chromosome 11 are involved in a majority of sporadic Wilms' tumours.Semantic proximity Read ↗

Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor.Semantic proximity Read ↗

Frequent loss of heterozygosity at 11p loci in testicular cancer.Semantic proximity Read ↗

Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.