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Article

Allelotyping in Wilms tumors identifies a putative third tumor suppressor gene on chromosome 11.

Genomics - 10 Jun 1995

Radice P, Perotti D, De Benedetti V, Mondini P, Radice M T, Pilotti S, Luksch R, Fossati Bellani F, Pierotti M A

Abstract excerpt

An analysis of loss of heterozygosity for markers on both the short and the long arm of chromosome 11 was performed in 24 sporadic Wilms tumors. Six cases (25%) showed allelic losses involving the entire chromosome. In one case (4%) the loss was restricted solely to the WT1 gene on band p13. Two cases (8%) displayed allelic losses for WT1 and for markers on band p15.5, where the putative tumor suppressor gene WT2...

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Source

Identifiers

PMID: 7558032
DOI: 10.1006/geno.1995.1082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Allelotyping in Wilms tumors identifies a putative third tumor suppressor gene on chromosome 11.PMID 7558032Read ↗

Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.Semantic proximity Read ↗

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Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters.Semantic proximity Read ↗

Loss of heterozygosity in Wilms' tumors, studied for six putative tumor suppressor regions, is limited to chromosome 11.Semantic proximity Read ↗

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