Differences in patterns of allelic loss between two common types of adult cancer, breast and colon carcinoma, and Wilms' tumor of childhood.

doi:10.1002/ijc.2910470604

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Article

Differences in patterns of allelic loss between two common types of adult cancer, breast and colon carcinoma, and Wilms' tumor of childhood.

International journal of cancer - 1 Apr 1991

Devilee P, van den Broek M, Mannens M, Slater R, Cornelisse C J, Westerveld A, Khan P M

Abstract excerpt

Several chromosomal regions exhibit loss of heterozygosity (LOH) in different types of human tumor, and on this basis are presumed to carry-suppressor genes. We studied 7 of such chromosome regions, including 3p, 5q, 11p, 13q, 17p, 18q and 22q, using a selected set of DNA markers in 44 Wilms' tum...

Topics

Adult
Alleles
Breast Neoplasms
Child
Chromosome Deletion
Colonic Neoplasms
DNA, Neoplasm
Female
Genes, Tumor Suppressor
Genetic Markers
Humans
Kidney Neoplasms
Polymorphism, Restriction Fragment Length
Rectal Neoplasms
Restriction Mapping
Wilms Tumor

Source

Open in PubMed

Identifiers

PMID: 1672665
DOI: 10.1002/ijc.2910470604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1672665-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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