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Article

Local spreading of MSL complexes from roX genes on the Drosophila X chromosome.

Genes & development - 1 Jun 2003

Oh Hyangyee, Park Yongkyu, Kuroda Mitzi I

Abstract excerpt

MSL proteins and noncoding roX RNAs form complexes to up-regulate hundreds of genes on the Drosophila male X chromosome, and make X-linked gene expression equal in males and females. Altering the ratio of MSL proteins to roX RNA dramatically changes X-chromosome morphology. In protein excess, the MSL complex concentrates near sites of roX transcription and is depleted elsewhere. These results support a model for...

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Identifiers

PMID: 12782651
DOI: 10.1101/gad.1082003
PMCID: PMC196065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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