Article

Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in <i>Drosophila testis</i>

2021-02-06

Abstract excerpt

Dosage compensation (DC) is a mechanism by which X chromosome transcription is equalized in the somatic cells of both males and females. In male fruit flies, expression levels of the X-chromosome are increased two-fold to compensate for their single X chromosome. In testis, dosage compensation is thought to cease during meiosis, however, the timing and degree of the resulting transcriptional suppression is difficu...

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Literature Corpus work: 95009804-f8ae-5b1a-a9d2-0489d18fce8f
DOI: 10.1101/2021.02.05.429952

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