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Article

Does the DRB1*1501 allele confer more severe and faster progression in primary progressive multiple sclerosis patients? HLA in primary progressive multiple sclerosis.

Journal of neuroimmunology - 29 Sept 2009

Vasconcelos Claudia Cristina Ferreira, Fernández Oscar, Leyva Laura, Thuler Luiz Claudio Santos, Alvarenga Regina Maria Papais

Abstract excerpt

The effect of HLA alleles on the outcome of multiple sclerosis (MS) has been widely investigated; however, results are conflicting and no consistent correlation has been established. This study evaluated the association between the HLA DR2 haplotype in patients with primary progressive MS (PPMS) and the effect of alleles on progression. An association was found between PPMS and the DR2 and DRB1*1501 and DQB1*0602...

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Source

Identifiers

PMID: 19616314
DOI: 10.1016/j.jneuroim.2009.06.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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