Article
HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study.
Genes and immunity - 1 Apr 2011
Liguori M, Healy B C, Glanz B I, Khoury S J, Moscufo N, Weiner H L, De Jager P L, Guttmann C R
Abstract excerpt
Several major histocompatibility complex (MHC) alleles have been postulated to influence the susceptibility to multiple sclerosis (MS), as well as its clinical/radiological course. In this longitudinal observation, we further explored the impact of human leukocyte antigen (HLA) class I/II alleles on MS outcomes, and we tested the hypothesis that HLA DRB1*1501 might uncover different strata of MS subjects...
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