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Article

A study of the HLA-DR region in clinical subgroups of multiple sclerosis and its influence on prognosis.

Journal of the neurological sciences - 1 May 1999

McDonnell G V, Mawhinney H, Graham C A, Hawkins S A, Middleton D

Abstract excerpt

OBJECTIVE: To investigate the HLA-DR associations in relapsing-remitting/secondary progressive multiple sclerosis (RR/SPMS) and primary progressive MS (PPMS). The HLA-DR2 allele (or its split, HLA-DRB1*15) is felt to be a risk factor for MS, rather than a genetic marker for the population of origin. Some studies have indicated a different HLA-DR antigen profile in PPMS patients compared with those having an...

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Source

Identifiers

PMID: 10426152
DOI: 10.1016/s0022-510x(99)00084-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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