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Article

The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta.

Journal of neuroimmunology - 1 Sept 2002

Villoslada Pablo, Barcellos Lisa F, Rio Jordi, Begovich Ann B, Tintore Mar, Sastre-Garriga Jaume, Baranzini Sergio E, Casquero Pilar, Hauser Stephen L, Montalban Xavier, Oksenberg Jorge R

Abstract excerpt

The HLA-DR2 haplotype (DRB1*1501, DQB1*0602) on chromosome 6p21 has consistently demonstrated both association and linkage with multiple sclerosis (MS) in case-control and family studies, particularly in Caucasians of Northern European descent. However, the role of a gene within this region in determining clinical features or response to immunotherapy remains largely unknown. A new familial MS data set from the...

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PMID: 12225902
DOI: 10.1016/s0165-5728(02)00215-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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