Article
HLA-DRB1 associations with disease susceptibility and clinical course in Australians with multiple sclerosis.
Tissue antigens - 1 Jul 2009
Stankovich J, Butzkueven H, Marriott M, Chapman C, Tubridy N, Tait B D, Varney M D, Taylor B V, Foote S J, Kilpatrick T J, Rubio J P
Abstract excerpt
Human leucocyte antigen (HLA)-DRB1*1501 and other class II alleles influence susceptibility to multiple sclerosis (MS), but their contribution if any to the clinical course of MS remains uncertain. Here, we have investigated DRB1 alleles in a large sample of 1230 Australian MS cases, with some enrichment for subjects with primary progressive (PPMS) disease (n = 246) and 1210 healthy controls. Using logistic...
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