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HLA-DRB11501, -DQB10301, -DQB10302, -DQB10602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis.

International review of neurobiology - 1 Jan 2007

Zivadinov Robert, Uxa Laura, Bratina Alessio, Bosco Antonio, Srinivasaraghavan Bhooma, Minagar Alireza, Ukmar Maja, Benedetto Su yen, Zorzon Marino

Abstract excerpt

The most important confirmed genetic factor of susceptibility to multiple sclerosis (MS) has been identified in the HLA class II region. The hypothesis that several genes, including HLA class II, may influence the prognosis of patients with MS has been proposed. In a recent study, using low intermediate resolution typing, we found that some HLA alleles may predict disease severity as assessed by magnetic...

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PMID: 17531857
DOI: 10.1016/S0074-7742(07)79023-2

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GML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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