Article
Characterization of a US sheep scrapie isolate with short incubation time.
Veterinary pathology - 1 Nov 2009
Hamir A N, Richt J A, Kunkle R A, Greenlee J J, Bulgin M S, Gregori L, Rohwer R G
Abstract excerpt
Scrapie is a naturally occurring fatal neurodegenerative disease of sheep and goats. Susceptibility to the disease is partly dependent upon the genetic makeup of the host. In a previous study it was shown that sheep intracerebrally inoculated with US scrapie inoculum (No. 13-7) developed terminal disease within an average of 19 months. We have since produced an inoculum, No. x124 from pooled brains of US-origin...
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