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Article

Disease phenotype of classical sheep scrapie is changed upon experimental passage through white-tailed deer.

PLoS pathogens - 1 Dec 2023

Kokemuller Robyn D, Moore S Jo, Bian Jifeng, West Greenlee M Heather, Greenlee Justin J

Abstract excerpt

Prion agents occur in strains that are encoded by the structure of the misfolded prion protein (PrPSc). Prion strains can influence disease phenotype and the potential for interspecies transmission. Little is known about the potential transmission of prions between sheep and deer. Previously, the classical US scrapie isolate (No.13-7) had a 100% attack rate in white-tailed deer after oronasal challenge. The...

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Identifiers

PMID: 38048370
DOI: 10.1371/journal.ppat.1011815
PMCID: PMC10721168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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