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Article

A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation.

The Journal of biological chemistry - 17 Jul 2009

Dickey Deborah M, Yoder Andrea R, Potter Lincoln R

Abstract excerpt

A heterozygous frameshift mutation causing a 12-amino acid extension to the C terminus of atrial natriuretic peptide (ANP) was recently genetically linked to patients with familial atrial fibrillation (Hodgson-Zingman, D. M., Karst, M. L., Zingman, L. V., Heublein, D. M., Darbar, D., Herron, K. J., Ballew, J. D., de Andrade, M., Burnett, J. C., Jr., and Olson, T. M. (2008) N. Engl. J. Med. 359, 158-165). The...

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Identifiers

PMID: 19458086
DOI: 10.1074/jbc.M109.010777
PMCID: PMC2740543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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