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Article

BNP molecular forms and processing by the cardiac serine protease corin.

Advances in clinical chemistry - 1 Jan 2013

Ichiki Tomoko, Huntley Brenda K, Burnett John C

Abstract excerpt

The cardiac hormone, B-type natriuretic peptide (BNP), is one of human natriuretic peptides which possesses cardiorenal protective actions and is used as a therapeutic and a biomarker for heart failure (HF). Its prohormone, proBNP1_108, is processed by the proNPs convertases, corin or furin, to inactive NT-proBNP1_76 and active BNP1-32. Paradoxically, circulating NT-proBNP and BNP are elevated in HF leading to...

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Identifiers

PMID: 24015598
DOI: 10.1016/b978-0-12-407680-8.00001-4
PMCID: PMC4522930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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