Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Haplotypes That Produce Normal Ficolin‐2 Levels Protect against Clinical Leprosy

26 Jan 2009

Abstract excerpt

Host factors have been shown to play a significant role in the susceptibility to and clinical outcome of leprosy. Here, we analyze polymorphisms of the gene encoding ficolin-2 (FCN2), which is a soluble pattern-recognition molecule. A total of 158 patients with leprosy and 210 healthy control subjects from Brazil were investigated. Polymorphisms in the promoter and exon 8 of FCN2 were assessed by DNA sequencing....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Leprosy Research and Treatment
Share to Lysosomal Storage Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19434912
DOI: 10.1086/597070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Haplotypes That Produce Normal Ficolin‐2 Levels Protect against Clinical LeprosyPMID 19434912Read ↗

Susceptibility to leprosy is associated with M-ficolin polymorphisms.Semantic proximity Read ↗

Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis.Semantic proximity Read ↗

Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy.Semantic proximity Read ↗

Ficolin 2 (FCN2) functional polymorphisms and the risk of rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease.Semantic proximity Read ↗

The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm.Semantic proximity Read ↗

Genetic variants of complement genes ficolin-2, mannose-binding lectin and complement factor H are associated with leprosy in Han Chinese from Southwest China.Semantic proximity Read ↗

Ficolin-2 levels and FCN2 haplotypes influence hepatitis B infection outcome in Vietnamese patients.Semantic proximity Read ↗

Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns.Semantic proximity Read ↗

The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels.Semantic proximity Read ↗

Ficolin-2 levels and genetic polymorphisms of FCN2 in malaria.Semantic proximity Read ↗

Ficolin-2 levels and FCN2 genetic polymorphisms as a susceptibility factor in schistosomiasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.