Article
Genetic variants of complement genes ficolin-2, mannose-binding lectin and complement factor H are associated with leprosy in Han Chinese from Southwest China.
Human genetics - 1 Jun 2013
Zhang Deng-Feng, Huang Xian-Qiong, Wang Dong, Li Yu-Ye, Yao Yong-Gang
Abstract excerpt
The complement system plays multiple roles in host defense against infection and is supposed to confer genetic susceptibility to leprosy. We aimed to examine whether genetic variants of the Ficolin-2 (FCN2), Mannose-binding lectin (MBL2) and Complement factor H (CFH) genes, which are involved in activation and regulation of the complement system, are associated with leprosy in Han Chinese from Southwest China....
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