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Article

Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis.

PloS one - 1 Jan 2012

Assaf Amal, Hoang Tong Van, Faik Imad, Aebischer Toni, Kremsner Peter G, Kun Jürgen F J, Velavan T P

Abstract excerpt

BACKGROUND: Ficolin-2 coded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity. In this study, we analyzed five functional polymorphisms of the FCN2 gene for their possible association with cutaneous leishmaniasis. METHODS: Initially we screened 40 Syrian Arabs for the entire FCN2 gene. We investigated the contribution of FCN2 functional variants in 226 patients with cutaneous...

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Source

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Identifiers

PMID: 22457818
DOI: 10.1371/journal.pone.0034113
PMCID: PMC3311577

Genes

FCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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