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Article

The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm.

The Journal of infectious diseases - 1 Nov 2007

de Messias-Reason Iara J, Boldt Angelica B W, Moraes Braga Anna Carolina, Von Rosen Seeling Stahlke Ewalda, Dornelles Luciana, Pereira-Ferrari Lilian, Kremsner Peter G, Kun Jurgen F J

Abstract excerpt

BACKGROUND: Mannan-binding lectin (MBL), a soluble protein of innate immunity, is known to play a role in pathogen recognition and clearance. For more than a decade, it has been proposed that MBL deficiency may be protective against intracellular pathogens, such as Mycobacterium leprae. METHODS: The polymorphisms at the promoter and exon 1 regions of the MBL2 gene were assessed by polymerase chain reaction and...

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Source

Identifiers

PMID: 17922403
DOI: 10.1086/521627

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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