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Article

Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy.

PLoS neglected tropical diseases - 1 Feb 2017

Andrade Fabiana Antunes, Beltrame Marcia Holsbach, Bini Valéria Bumiller, Gonçalves Letícia Boslooper, Boldt Angelica Beate Winter, de Messias-Reason Iara Jose

Abstract excerpt

Leprosy is a chronic inflammatory disease caused by Mycobacterium leprae that mainly affects the skin and peripheral nervous system, leading to a high disability rate and social stigma. Previous studies have shown a contribution of genes encoding products of the lectin pathway of complement in the modulation of the susceptibility to leprosy; however, the ficolin-3/FCN3 gene impact on leprosy is currently unknown....

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Source

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Identifiers

PMID: 28241035
DOI: 10.1371/journal.pntd.0005409
PMCID: PMC5344521

Genes

FCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy.PMID 28241035Read ↗

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Adding <i>MASP1</i> to the lectin pathway – leprosy association puzzle: hints from gene polymorphisms and protein levelsSemantic proximity Read ↗

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